Azure ExpressRoute Region Question for Network Edge

When connecting more ExpressRoute circuits into our Equinix Network Edge, does the region of the Azure ExpressRoute matter?

For example, if we have an existing ExpressRoute in Azure CentralUS peered with Equinix Network Edge in Chicago and wanted to add another ExpressRoute out of Azure West. Can it also be peered with our existing Network Edge Cisco 8000Vs in Chicago?